Дифензокват

Description

Diphenzoquat is a herbicide of the class of pyrazolium derivatives in the form of a free cation (1,2-dimethyl-3,5-diphenyl-1H-pyrazolium), the starting compound for salt forms, including methyl sulfate. The active ingredient of the drug Avenge CP.

Basic Attributes

• CAS No.: 49866-87-7
• Chemical formula: C17H17N2
• English name: Difenzoquat
• Molecular weight: 249.33; exact mass: 249.139
• EU number: 256-505-3
• UNII: 54NE792QN5
• DSSTox ID: DTXSID6043965
• PSA Specifications: 8.8
• XLogP3: 3.1836

Mechanism of action and scope of application

Like the methyl sulfate salt, the free diphenzoquat cation acts as a selective post-emergence herbicide against wild oats in wheat and barley crops: it is absorbed by the leaves, moves to the growth point and destroys cell membranes, inhibiting the division and elongation of cells of the apical and internodal meristem of the weed.

Toxicity and fire hazard

Oral LD50 in rats: 470 mg/kg. When burned, toxic gaseous oxides of nitrogen and sulfur are formed.

Safety Information

• Packing level: III
• Hazard category: 6.1(b)
• Transport codes: 2588

Storage and transportation

The warehouse is ventilated, with low temperature and dry air; stored and transported separately from food materials. Wear gloves and safety glasses.

Comparison with methyl sulfate salt

Compared to the methyl sulfate salt (CAS 43222-48-6), the free diphenzoquat cation has a lower molecular weight (249.33 versus 360.43) due to the absence of the methyl sulfate counterion; the LD50 value for the free cation is higher (470 mg/kg versus 270 mg/kg for methyl sulfate), indicating a slightly lower acute oral toxicity of the cation without a counterion.

Chemical class

The pyrazolium cation belongs to the group of quaternary aromatic heterocyclic cations that are resistant to dissociation into neutral forms; This structure is typical for herbicides with rapid systemic movement through the phloem and xylem of the plant after penetration through the leaf cuticle.

Batch identification

When ordering, check the batch against CAS number 49866-87-7, EC number 256-505-3 and UNII 54NE792QN5 - commercial preparations based on the free cation are less common than the methyl sulfate salt, due to the more difficult to obtain storage-stable form.

Delivery form

Supplied under the trade name Avenge CP, usually in the form of a soluble concentrate; the concentration of the active substance depends on the specific formulation of the manufacturer.

Technological features

The free cation of diphenzoquat is hygroscopic, like most ionic pyrazolium compounds, and is more often used commercially as the more stable methyl sulfate salt (CAS 43222-48-6), where the counterion reduces the sensitivity of the product to moisture during concentrate storage.