Этилдихлортиофосфат

Description

Ethyldichlorothiophosphate (O-ethylphosphorodichloridothionate) is an acid chloride of thiophosphoric acid, an intermediate product of pesticide chemistry. The molecule carries two reactive P–Cl bonds and one ethoxy group P–O–Et at the thione sulfur atom P=S. Chlorine in such compounds is easily replaced by nucleophiles - alcohols, phenols and amines, so the substance serves as a building block for the introduction of a thiophosphate group into the target molecule of the active substance.

Basic Attributes

• CAS No.: 1498-64-2
• Chemical formula: C2H5Cl2OPS
• Molecular weight: 179.01
• Exact weight: 179.01
• EU number: 216-100-4
• NSC Number: 91481
• DSSTox ID: DTXSID6061733
• HS code: 2931900090
• PSA specifications: 41.3
• XLogP3: 3.3756

Synonyms

Phosphorodichloridothionic acid, O-ethyl ester; phosphine sulfide dichloroethoxy; ethyl dichlorothiophosphate; ethylphosphonodichloridothionate; O-ethylphosphorodichloridothioate; O-ethyl dichlorothiophosphate; (dichloroethoxy)phosphine sulfide; NSC 91481.

Physico-chemical characteristics

• Density: 1.3968 g/cm3 at 0 °C
• Boiling point: 52 °C at residual pressure 10 Torr
• Flash point: above 230°F
• Refractive index: n20/D 1.504 (lit.)
• Steam pressure: 10 mm Hg. Art. at 55 °C

Scope of application

The product belongs to the intermediate compounds of pesticide chemistry: by the reaction of chlorine with phenols, thiols or amines, the active substances of organophosphorus insecticides and acaricides of the thiophosphate group are built from it, in which the P=S group provides the necessary selectivity of action on the cholinesterase of insect pests. Additionally, ethyldichlorothiophosphate is used as a reagent for introducing the O-ethylthiophosphate fragment into molecules in the synthesis of fire retardants and other phosphorus-containing additives.

Safety Information

• Packing level: II
• Hazard category: 6.1(a)
• Transport codes: UN 3390, 6.1/page. 1
• WGK Germany: 3
• Hazard class code: 23/24/25-34-23/24-22
• Safety instructions: 22-26-36/37/39-45
• RTECS number: TD4400000
• Tags: T
• Hazard statements: H302, H311, H314, H331
• Precautions: P261, P280, P305 + P351 + P338, P310
• GHS classification: hazardous, H302 (100%) - harmful if swallowed; full list of classification precautions: P260, P261, P264, P270, P271, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P311, P312, P321, P322, P330, P361, P363, P403+P233, P405, P501; aggregated information provided by 38 companies from 1 notification to the ECHA C&L Register

Storage and transportation conditions

The reagent is sensitive to moisture: contact with water causes hydrolysis of P–Cl bonds with the release of hydrogen chloride, so the container is kept hermetically sealed, in a dry, cool, ventilated room, away from water, alcohols, amines and bases. Transport - Packing Group II, UN 3390, Hazard Category 6.1(a). Wear gloves, safety glasses and respiratory protection; in case of spills, do not allow moisture to come into contact with the product.