Бутиронитрил

69.11

69.11

1361452

203-700-6

O3V36V0W0M

1465

8412

2411

DTXSID1026823

Colorless liquid

29269095

23.8

0.5/0.6

Clear Liquid

0.8091 g/cm³ @ Temp: 0 °C

-112 °C

117.5 °C @ Press: 760 Torr

62 °F

n20/D 1.384(lit.)

Miscible with benzene, alcohol, ether and dimethylformamide. Slightly soluble in water.

Flammables area

23 mm Hg ( 25 °C)

2.4 (vs air)

Oral-rat LD50: 50 mg/kg;Oral-Mouse LD50: 27.689 mg/kg

In case of heat, open flame, oxidant is flammable; high heat releases nitrogen oxide, cyanide gas

vol% in air: 1.6

Sharp, suffocating odor.

5.23e-05 atm-m3/mole|Henry's Law constant = 5.23X10-5 atm cu m/mole @ 25 °C

Dipole moment: 3.5|Standard heat of formation: -5.82 kJ/mol @ 25 °C (liquid), 33.97 kJ/mol @ 25 °C (gas)

Highly flammable. Slightly soluble in water.

Nitriles

Highly Flammable

BUTYRONITRILE can react vigorously with oxidizing reagents, when heated to decomposition, it emits highly toxic fumes of cyanides and oxides of nitrogen [Sax, 9th ed., 1996, p. 609]. Nitriles may polymerize in the presence of metals and some metal compounds. They are incompatible with acids; mixing nitriles with strong oxidizing acids can lead to extremely violent reactions. Nitriles are generally incompatible with other oxidizing agents such as peroxides and epoxides. The combination of bases and nitriles can produce hydrogen cyanide. Nitriles are hydrolyzed in both aqueous acid and base to give carboxylic acids (or salts of carboxylic acids). These reactions generate heat. Peroxides convert nitriles to amides. Nitriles can react vigorously with reducing agents. Acetonitrile and propionitrile are soluble in water, but nitriles higher than propionitrile have low aqueous solubility. They are also insoluble in aqueous acids.

910 °F (USCG, 1999)|935 °F (501 °C)|501 °C

-2568.68 kJ/mol @ 25 °C

11.67 eV

LOWER FLAMMABLE LIMIT: 1.65%|Class IB Flammable Liquid: Fl.P. below 73°F and BP at or above 100°F.

The vapour mixes well with air, explosive mixtures are easily formed.

39.33 kJ/mol @ 25 °C

Critical temperature: 309.1 °C; critical pressure: 37.4 atm

II

3

UN 2411 3/PG 2

1

10-23/24/25-11

45-63-36/37-16

ET8750000

T,F

The warehouse is ventilated, low temperature and dry; stored separately from oxidants and acids

Toxic

Explosive when mixed with air

Stable. Combustible. Substances to be avoided include strong acids, strong bases, strong oxidizing agents and strong reducing agents.

P210-P261-P280-P301 + P310-P311

H225-H301 + H311 + H331

Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste numbers D003 and P030 must conform with USEPA regulations in storage, transportation, treatment and disposal of waste. /Cyanide cmpd and Cyanides, not otherwise specified/|A poor candidate for incineration. /Cyanides/

Strong oxidizers & reducing agents, strong acids & bases.|Dangerous fire hazard when exposed to heat, flame, or oxidizers.

Special Hazards of Combustion Products: Toxic cyanide fumes (USCG, 1999)|Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire. Above 17 °C explosive vapour/air mixtures may be formed.|Flammable - 3rd degree

|Danger|H225: Highly Flammable liquid and vapor [Danger Flammable liquids]|P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P280, P301+P310, P302+P352, P303+P361+P353, P304+P340, P311, P312, P321, P322, P330, P361, P363, P370+P378, P403+P233, P403+P235, P405, and P501|H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]|Aggregated GHS information provided by 149 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|P210, P233, P240, P241, P242, P243, P260, P264, P270, P271, P280, P284, P301+P310, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P307+P311, P310, P312, P320, P321, P322, P330, P337+P313, P361, P363, P370+P378, P403+P233, P403+P235, P405, and P501

Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]: As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]: Fully encapsulating, vapor-protective clothing should be worn for spills and leaks with no fire. ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. SMALL SPILL: Absorb with earth, sand or other non-combustible material and transfer to containers for later disposal. Use clean, non-sparking tools to collect absorbed material. LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces. (ERG, 2016)

Skin: Wear appropriate personal protective clothing to prevent skin contact. Eyes: Wear appropriate eye protection to prevent eye contact. Wash skin: The worker should immediately wash the skin when it becomes contaminated. Remove: Work clothing that becomes wet should be immediately removed due to its flammability hazard(i.e. for liquids with flash point Change: No recommendation is made specifying the need for the worker to change clothing after the work shift. Provide: Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure. [Note: It is intended that these facilities provide a sufficient quantity or flow of water to quickly remove the substance from any body areas likely to be exposed. The actual determination of what constitutes an adequate quick drench facility depends on the specific circumstances. In certain instances, a deluge shower should be readily available, whereas in others, the availability of water from a sink or hose could be considered adequate.] (NIOSH, 2016)|Wear appropriate personal protective clothing to prevent skin contact.|Wear appropriate eye protection to prevent eye contact.|Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure. [Note: It is intended that these facilities provide a sufficient quantity or flow of water to quickly remove the substance from any body areas likely to be exposed. The actual determination of what constitutes an adequate quick drench facility depends on the specific circumstances. In certain instances, a deluge shower should be readily available, whereas in others, the availability of water from a sink or hose could be considered adequate.]|Recommendations for respirator selection. Max concn for use: 80 ppm. Respirator Class(es): Any chemical cartridge respirator with organic vapor cartridge(s). Any supplied-air respirator.|For more Personal Protective Equipment (PPE) (Complete) data for BUTANENITRILE (9 total), please visit the HSDB record page.|(See protection codes)

FLAMMABLE, DANGEROUS FIRE RISK.|Dangerous fire hazard when exposed to heat, flame, or oxidizers.

Explosive limits , vol% in air: 1.6-?

ALCOHOL FOAM.|If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped or safely confined. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use "alcohol" foam, dry chemical or carbon dioxide.

The worker should immediately wash the skin when it becomes contaminated.|Work clothing that becomes wet should be immediately removed due to its flammability hazard.|N-butyronitrile is considered highly toxic and requires the same handling as other toxic nitriles.|All nitriles should be handled under carefully controlled conditions and only by personnel having a thorough understanding and knowledge of safe handling techniques. Because of the nature of nitrile cmpd and the lack of complete toxicity data on many nitriles, care should be exercised in handling these cmpd to avoid inhalation of the vapors, ingestion, and contact with the skin. /Nitriles/|For more Preventive Measures (Complete) data for BUTANENITRILE (7 total), please visit the HSDB record page.

/GUIDE 131: FLAMMABLE LIQUIDS - TOXIC/ Fire or Explosion: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion and poison hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.|/GUIDE 131: FLAMMABLE LIQUIDS - TOXIC/ Health: TOXIC; may be fatal if inhaled, ingested or absorbed through skin. Inhalation or contact with some of these materials will irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.|/GUIDE 131: FLAMMABLE LIQUIDS - TOXIC/ Public Safety: CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate closed spaces before entering.|/GUIDE 131: FLAMMABLE LIQUIDS - TOXIC/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.|For more DOT Emergency Guidelines (Complete) data for BUTANENITRILE (8 total), please visit the HSDB record page.

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

A skin irritant.

Recommended Exposure Limit: 10 Hr Time-Weighted avg: 8 ppm (22 mg/cu m).

Remove all ignition sources. Personal protection: self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

Fireproof. Separated from strong oxidants, strong reducing agents, strong bases, strong acids and food and feedstuffs. Keep in a well-ventilated room.

A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20 °C , on spraying or dispersing much faster.

The vapour is mildly irritating to the eyes, skin and respiratory tract. The substance may cause effects on the cellular respiration (inhibition). This may result in convulsions, cardiac disorders and respiratory failure. Exposure at high levels could cause death. The effects may be delayed. Medical observation is indicated.

NO open flames, NO sparks and NO smoking. NO contact with oxidizing agents. Above 17 °C use a closed system, ventilation and explosion-proof electrical equipment. Do NOT use compressed air for filling, discharging, or handling.

STRICT HYGIENE! IN ALL CASES CONSULT A DOCTOR!

Use ventilation, local exhaust or breathing protection.

Protective clothing. Protective gloves.

Wear face shield or eye protection in combination with breathing protection.

This action promulgates standards of performance for equipment leaks of Volatile Organic Compounds (VOC) in the Synthetic Organic Chemical Manufacturing Industry (SOCMI). The intended effect of these standards is to require all newly constructed, modified, and reconstructed SOCMI process units to use the best demonstrated system of continuous emission reduction for equipment leaks of VOC, considering costs, non air quality health and environmental impact and energy requirements. Butyronitrile is produced, as an intermediate or a final product, by process units covered under this subpart.

| 3 - Materials that, under emergency conditions, can cause serious or permanent injury.| 3 - Liquids and solids that can be ignited under almost all ambient temperature conditions. Materials produce hazardous atmospheres with air under almost all ambient temperatures or, though unaffected by ambient temperatures, are readily ignited under almost all conditions.| 0 - Materials that in themselves are normally stable, even under fire conditions.

A product water effluent from a coal gasification facility in Hanna, WY was found to contain a butanenitrile concn of 267 ppb(1); retort water from a shale-oil processing facility in Rock Springs, WY contained a butanenitrile concn of 13 ppb(1). The concn of propionitrile in condensate retort water from an oil-shale processing facility in Colorado was 2.5 mg/l(2).