Метилхафрутикозинат

Description

Methylhafruticosinate (methylhanofruticosinate) is an indole alkaloid of the methylhanofruticosinate group. Compounds of this series are isolated from plants of the genus Kopsia of the Kutrov family, widespread in tropical Asia: findings are described in the leaves of Kopsia arborea, in the grass of Kopsia officinalis, in Kopsia flavida and Kopsia lancibracteolata. Methylhanofruticosinate from Kopsia officinalis showed weak activity against HIV-1. The product is supplied as a reference standard for phytochemical analysis and screening studies.

Basic Attributes

• CAS No.: 14050-92-1
• Chemical formula: C23H26N2O5
• Molecular weight: 410.5
• Exact weight: 410.184174
• PSA specifications: 76.15000
• XLogP3: 3.31
• Synonyms: methyl hafruticosinate, methyl hanofruticosinate

Physico-chemical characteristics

• Density: 1.40 ± 0.1 g/cm3 (calculated value)
• Boiling point: 558.5 ± 50.0 °C (calculated value)
• Flash point: 291.6 ± 30.1 °C
• Refractive index: 1.654

Density and boiling points are based on predictive models rather than direct measurements. The polar surface of 76.15 Å2 and XLogP3 of 3.31 indicate a moderately lipophilic molecule with several oxygen-containing groups.

Scope of application

• analytical standard for studying the alkaloid composition of plants of the genus Kopsia
• object of work on the chemistry of indole alkaloids with a rare carbon skeleton
• material for biological screening, including antiviral tests

Storage and handling

The alkaloid is supplied in small portions. Keep the container closed, in a dry place, away from light. Work with gloves, avoid inhalation of dust and contact with skin: the toxicological profile of the substance has not been fully studied, handle as a biologically active compound.