Гесперидинметилхалькон

Description

Hesperidin methylchalcone (HMC) is a citrus bioflavonoid obtained by methylation of hesperidin to open the flavanone ring to the chalcone form. Unlike the original hesperidin, it is soluble in water, which determines its demand in formulations. INCI name: Hesperidin Methyl Chalcone. Yellow powder. The systematic designation is 2-propen-1-one, 1-[4-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-hydroxy-6-methoxyphenyl]-3-(3-hydroxy-4-methoxyphenyl)-, (2E)-.

Basic Attributes

• CAS No.: 24292-52-2
• Chemical Formula: C29H36O15
• Molecular weight: 624.59 (in the original card the value is given without a separator - 62459)
• Exact weight: 624.59
• EU number: 246-128-2
• UNII: 4T2GVA922X
• PSA Specifications: 234
• XLogP3: 1.86
• Appearance: yellow powder
• Density: 1.6 ± 0.1 g/cm³
• Melting point: 120 °C with decomposition (the card said “December” - an artifact of the machine translation of the abbreviation dec.)
• Boiling point: 953.0 ± 65.0 °C at 760 mm Hg. Art.
• Flash point: 309.5 ± 27.8 °C
• Refractive index: 1.672
• Storage conditions: 2–8 °C
• RTECS number: FL7085000

Purpose and areas of application

The main consumer is the cosmetics industry, the direction of care for the area around the eyes and skin with a pronounced vascular pattern.

• products for the eyelids and areas under the eyes: reducing the severity of dark circles, working with puffiness
• care for facial skin with vascular manifestations: strengthening capillary walls, reducing capillary permeability
• antioxidant function in the recipe: suppression of oxidative processes, protection against rancidity
• component of the finished active complex Eyeliss in conjunction with Dipeptide-2 and Palmitoyl Tetrapeptide-7 - the complex is addressed to bags under the eyes
• anti-aging compounds

The starting material is hesperidin from sweet orange peel. Methylation converts the sparingly soluble flavanone into a water-soluble chalcone form, which allows the substance to be introduced into the aqueous phases of emulsions and gels.

Safety Information

• Transport codes: NONH for all types of transport (not classified as dangerous goods)
• WGK Germany: 3
• RTECS number: FL7085000

Storage and handling

Temperature range 2–8 °C, container tightly closed, access to light and moisture limited. The powder decomposes at 120 °C, so it is introduced into the formulation at the cooling stage, and not in the hot phase. Water hazard class WGK Germany 3 requires that residues and rinsing water not be discharged into the sewer system. Hazard statements and hazard class codes are not provided on the original card; When hanging the powder, use gloves, goggles and local exhaust.