Ксантинин

Description

Xanthinine is a sesquiterpene lactone of the xanthanolide group from plants of the genus Xanthium (cocklebur), isolated from Xanthium pennsylvanicum. Xanthanolides are a characteristic group of sesquiterpenoids of this genus; With the discovery of xanthate and xanthinin, a systematic study of the entire family began; today, more than thirty such compounds have been described from Xanthium species. Xanthinine has the properties of a plant growth regulator and phytotoxicity - it inhibits plant growth. Pharmacological works behind it describe anti-inflammatory effects, effects on the formation of bile acids in the liver with a decrease in cholesterol and triglycerides, as well as antitumor effects.

Basic Attributes

• CAS No: 153483-31-9
• Chemical formula: C17H22O5
• Molecular Weight: 306.358
• Exact weight: 306.146729
• PSA specifications: 69.7
• XLogP3: 1.95

Physico-chemical characteristics

• Density: 1.2 ± 0.1 g/cm3
• Boiling point: 476.3 ± 45.0 °C at 760 mm Hg. Art.
• Flash point: 210.6 ± 28.8 °C
• Refractive index: 1.513

Structure

Systematic designation: [1-(7-methyl-3-methylidene-2-oxo-4,7,8,8a-tetrahydro-3aH-cyclohepta[b]furan-6-yl)-3-oxobutyl]acetate. In the molecule, the α-methylene-γ-butyrolactone fragment, acetoxy group and ketone - it is the exocyclic methylene group at the lactone that determines the reactivity of xanthanolides.

Scope of application

• research on plant growth regulators and allelopathy
• standard sample for the analysis of xanthanolides in Xanthium raw materials
• pharmacological work on the anti-inflammatory and antitumor activity of sesquiterpene lactones

Storage and handling

The container is tightly closed, a cool, dry place, limited light. Compounds with an α-methylene lactone moiety react with thiols and amines, so co-storage with such substances is avoided. Wear gloves: Sesquiterpene lactones of this type are known as contact sensitizers. GHS classification and transport codes are not given in the supplier card.