Китайский порошок B

Substance identification

Chinese B powder (Chinensine B) is a natural labdane-type diterpenoid isolated from the rhizome of Alpinia chinensis (ginger). The name "Chinese Powder B" is a literal translation of the English Chinensine B, reflecting the origin of the compound from a plant with the species epithet chinensis, and not an indication of the physical form of the powder.

Basic Attributes

• CAS No: 849245-34-7
• Chemical formula: C20H28O3
• English name: Chinensine B
• Molecular Weight: 316.43452
• Exact weight: 316.203857
• PSA: 46.5
• XLogP3: 4.31

Physico-chemical characteristics

• Density: 1.1±0.1 g/cm3
• Boiling point: 475.2±45.0 °C at 760 mm Hg. Art.
• Flash point: 191.9±21.5°C
• Refractive index: 1.549

Substance class

According to the systematic name 16-hydroxylabda-8(17),11,13-trien-15,16-olide, the compound belongs to the diterpenoids of the labdane series (C20-terpenoids) with a lactone ring - a chemically larger molecule than sesquiterpenes (C15), which is reflected in the Russian-language section of the “Terpenes” catalog.

Botanical source and related compounds

Isolated from the rhizome of Alpinia chinensis along with the related diterpenoids quinensines A, C, D and E, described as antitumor compounds of this plant source.

Biological activity

Quinensines, including quinensine B, have been described in the literature as antitumor diterpenoids; The specific mechanisms of antitumor action and data from preclinical trials specifically for quinensine B are not detailed in the available sources, so a general conclusion about the antitumor nature of the compound does not replace the missing quantitative data on effectiveness.

Application

Reference standard and object of research in the phytochemistry of Alpinia chinensis diterpenoids, as well as in screening the antitumor activity of natural compounds.

Missing data

Solubility, storage conditions, vapor pressure, toxicological parameters (LD50), GHS phrases and UN transport codes are not published by the supplier and are not found in open sources.

Storage and transportation

Numerical storage and transportation parameters are not specified by the supplier. As a compound with a lactone cycle, potentially sensitive to hydrolysis, the substance is by default stored in containers protected from light and moisture.

Features of title translation

The Russian name “Chinese Powder B” in the catalog is the result of a literal machine translation of the English Chinensine B, where “Chinensine” is derived from the species epithet chinensis of the source plant, and not from the word “Chinese powder” as the physical form of the substance; a more accurate name would be quinensine B.

Chemical class of diterpenoids

Diterpenoids (C20) are a larger structural class of terpenoids compared to sesquiterpenes (C15, which includes most other Chloranthus compounds in this catalog line); The labdane skeleton is one of the most common types of diterpene cyclization in the plant world.